This teaches you not only how to use AutoDock 4 to perform virtual screening using AutoDock 4, but also a lot about using UNIX to organize and process large numbers of files, skills that are transferable to many other problems. There is one PDF file (Handout) with step-by-step instructions, and another with the slides that accompany the presentation. The Handout includes instructions on how to download the necessary input files. When we teach this tutorial, we require that you have attended the "Using AutoDock 4 with AutoDockTools" tutorial.